Research / MIDL 2023, short paper

Improving Zero-Shot Detection of Low Prevalence Chest Pathologies using Domain Pre-trained Language Models

Aakash Mishra, Rajat Mittal, Christy Jestin, Kostas Tingos, Pranav Rajpurkar

MIDL 2023, short paper · Apr 2023

An image tower paired with a BERT text tower whose weights come from transformers pre-trained on MIMIC-III and PubMed
An image tower paired with a BERT text tower whose weights come from transformers pre-trained on MIMIC-III and PubMed

Swapping a CLIP model's text tower for one pre-trained on clinical text hurts on common chest findings but helps a lot on rare ones.

Abstract

Recent advances in zero-shot learning have enabled the use of paired image-text data to replace structured labels, removing the need for expert-annotated datasets. Models such as CLIP-based CheXzero use these advances for chest X-ray interpretation.

We hypothesize that domain pre-trained models such as CXR-BERT, BlueBERT, and ClinicalBERT can improve CLIP-like models with domain knowledge by replacing BERT weights, at the cost of breaking the original model's alignment. We evaluate zero-shot classification models with domain-specific pre-training for detecting low-prevalence pathologies. Even though replacing the weights of the original CLIP-BERT degrades performance on common pathologies, pre-trained text towers perform much better on low-prevalence diseases. This motivates future ensembles that combine differently trained language models.

Cite

@inproceedings{mishra2023improving,
  title = {Improving Zero-Shot Detection of Low Prevalence Chest Pathologies using Domain Pre-trained Language Models},
  author = {Aakash Mishra and Rajat Mittal and Christy Jestin and Kostas Tingos and Pranav Rajpurkar},
  year = {2023},
  booktitle = {Medical Imaging with Deep Learning, short paper track},
  eprint = {2306.08000},
  archivePrefix = {arXiv}
}